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Old English original apothecary (or modern-day pharmacist) "Dispensing" sign. In addition to dispensing herbs and medicine, the apothecary offered general medical advice and a range of services.  In seventeenth century England, they also controlled the trade of tobacco which was imported as a medicine. 

Reverse painted glass.

A different connotation entirely might be thought of in modern day California...

Dimensions: 17 x 5

Circa: 1900

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